Describe the structural difference of steroids and cholesterol?
steroid is a lipid whose structure is base on the tetracyclic structure. The
steroid structure have four rings . it have three cyclohexane ring and 1
is the major sterol in the animal tissues. sterol is also a form of steroid but with
eight to ten carbon atoms in the chain at C-17 and a hydroxyl group at C-3.
also has four rings like steroid but
it has an eight carbon branched hydrocarbon chain which is attached to C-17
of the D ring and the ring A has a hydroxyl group at C-3 and the ring B has a
double bond between C-5 and C-6.
QNO:2 Differentiate between bile
acids and bile salts?
Bile is a fluid that is
made and free by the liver and stored in the gallbladder. Bile also help in the
lipid digestion. Bile consists of a dilute mixture of organic and inorganic
Bile acids are steroid acids which are found mainly in the bile of mammals
and other vertebrates.
acids are conjugated with taurine or glycine in the liver and the potassium
and sodium salts of these conjugated bile acids are called bile salts. These
are most significant organic compounds of bile.
The bile acids contain the 24 carbons with 2 or 3 hydroxyl groups. And a side
chain that terminates in a carboxyl group. Bile acids are synthesized in the
liver by the multistep. a multiorganelle pathway in which a hydroxyl groups
are inserted specific positions on the steroid structure and the double bound
of the cholesterol B ring is reduced. And the hydrocarbon chain is reduced by
three carbons. The most common resultant compounds are the cholic acid and
the chenodeoxycholic acid called a primery bile acid.
the synthesis of bile salts, before leaving the liver the bile acids are
conjugated to a molecule of glycine or tourine by an amide bond between the
carboxyl group of the bile acid and the amino group of the other compound. These
new structure are called bile salts and contain glycocholic acids and
Example cholic acids and chenodeoxycholic
Glycine and tourine.