For analysis of QoL,some questionnaires were prepared exclusivelyfor patients suffering from Parkinson’s disease (PD). The best known aretwo scales, Parkinson `s Disease Questionnaire (PDQ-39) and Parkinson` sDisease Quality of Life Questionnaire (PDQL), are less frequently used scalesthan PDQUALIF PIMS. Martinez-Martin believes that the quality of life scalesare more useful than other scales in evaluating the results of rehabilitationand drug treatment of Parkinson’s disease or neurosurgery 7.
Hence, Parkinson’s Disease Questionnaire- 39 is beingused in this study. Therefore, analysis ofthe severity of any disease should include not only the clinical factors butalso the psychological & social factors pertaining with the patient.Parkinson’s Disease has a profound negative impact on the Quality of Life (QoL)as pointed out by numerous studies, patients suffer from fatigue, dementia,emotional problems, sleep disorders, difficulty in speech and balance,depression, diminished cognitive functions and several other lifestyle changes6. Quality of Life (QoL) isa multi-dimensional construct, which consists of at least three main domains:physical, mental and social. In medicinal sciences, health-related quality oflife concept is often used by researchers and scientists. It concentrates onthe impact of the disease and/or treatment on patients’ perception of their lifestyleand on subjective well-being or satisfaction with life 5. Patients are usually prescribedLevodopa, COMT Inhibitors, Dopamine Agonists, Non-Dopaminergic Therapy, etc3.
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Therefore, assessing of prescriptions associated to the disease is necessaryto improve the therapeutic efficacy and to reduce the side effects & toprovide feedback to the prescribers. The main aim of this drug utilizationstudy is to facilitate rational drug use and knowing the efficacy of each oneof them 4. The rampancy of thedisease ranges from 41 people per 100,000 in the fourth decade of life to morethan 1,900 people per 100,000 among those 80 and older 2. Parkinson’s disease (PD)belongs to a group of neurodegenerative conditions called motor system diseases,which are the result of the loss of dopaminergic brain cells. The primarysymptoms of PD are tremor, or trembling in limbs, jaw, and face rigidity, orstiffness of the limbs and slowness of trunk movement, postural instability, orimpaired balance and coordination 1.